ChemInform Abstract: Synthesis of Optically Active Oxazoline Derivatives via Catalytic Asymmetric Desymmetrization of 1,3‐Diols.

Abstract

Desymmetrization of 1,3-Diols. -The procedure is applicable to various amino--1,3-diols tolerating (hetero)aryl substituents bearing electron-donating as well as electron-withdrawing groups, and moieties. The products are mostly obtained with high enantioselectivities. -(TSUDA, Y.; KURIYAMA, M.; ONOMURA*, O.; Chem. Eur. J. 18 (2012) 9, 2481-2483, http://dx.doi.org/10.1002/chem.201103800 ; Grad. Sch. Biomed. Sci., Nagasaki Univ., Nagasaki 852, Japan; Eng.) -S. Adam 29-129