ChemInform Abstract: Synthesis of New Aza‐Bicyclic 2‐Isoxazolines by 1,3‐Dipolar Cycloaddition of Endocyclic Enecarbamates and Enamides with Nitrile Oxides.

Abstract

Isoxazole derivatives R 0240Synthesis of New Aza-Bicyclic 2-Isoxazolines by 1,3-Dipolar Cycloaddition of Endocyclic Enecarbamates and Enamides with Nitrile Oxides. -Various target compounds, which are of interest as synthons of alkaloids or pharmaceuticals, are prepared following the title reaction. Some further transformations of the products are also studied. -(DE ALMEIDA, V. M.; DOS SANTOS, R. J.; DA SILVA GOES, A. J.; DE LIMA, J. G.; CORREIRA, C. R. D.; DE FARIA*, A. R.; Tetrahedron Lett. 50 (2009) 6, 684-687; Dep. Cienc. Farm., Univ. Fed. Pernambuco, 50740 Recife, Pernambuco, Brazil; Eng.) -Mais 20-117