ChemInform Abstract: Synthesis of Multi‐Substituted 2‐Iminopyridine by Conjugate Addition of Ethyl Cyanoacetate Derivatives to Alkynyl Imines.

Abstract

Alkynyl Imines. -Highly functionalized title compounds are obtained in the presence of excess KN(Tms)2. Deprotection with TfOH leads to 2-aminopyridines. The method can also be applied for the construction of bicyclic compounds [cf. (VI)]. -(HACHIYA, I.; MINAMI, Y.; ARAMAKI, T.; SHIMIZU*, M.; Eur.