ChemInform Abstract: Synthesis of Labeled Fatty Acids with or without Substituted αor β‐Positions.

Abstract

The title compounds, e.g. (VII), (X) and (XV), are prepared for kinetical studies of their metabolism.

Preparation of 99mTc Nitrido Core β-Diketonate Complexes for Radiopharmaceuticals

“…Isolation steps in Method I are assumed to be responsible for lowering the yield, in particular the evaporation step of the acid Solution containing the intermediate [^^'"TcNCl^ ] before the addition of ^-diketone ligand results in large loss. Apparu et al [17] reported that ^^'"TcNCU at pH > 4 transforms rapidly in ^^'"TcOj. As noted by Comazzi et al [12] the evaporation steps for both the starting aqueous Solution of pertechnetate and the Solution containing the intermediate [''""TcNCl^] in the azide method do not permit careful control of the sterility and apytogenicity, so method I does not appear to be so applicable to diagnostic nuclear medicine.…”