ChemInform Abstract: Synthesis of Glycol Monoesters by Oxidation of 1,3‐Dioxacyclanes.

An improved protocol for aerobic oxidation of acetals to esters catalyzed by N-hydroxy phthalimide (NHPI) and lipophilic Co(II) complexes

“…Although, there is a limited number of procedures on the oxidation of cyclic acetals by H 2 O 2 , t-BuOOH, and stoichiometric oxidizing agents [3][4][5][6][7][8][9][10][11][12][13][14], in particular, their oxidations with O 2 via a radical process is rarely reported [15]. Thus, we decided to expand the domain of this new protocol over the oxidation of various types of cyclic acetals.…”

“…Along this line, the utilization of molecular oxygen as final oxidant in oxidation process has been becoming increasingly attractive in recent years. Unfortunately, despite the importance and attractiveness of this opinion, less attention has been paid to the development of new protocols for efficient oxidations of acetals to the corresponding ester using molecular oxygen [15].…”

Efficient Aerobic Oxidation of Acetals to Esters Catalyzed byN-Hydroxy phthalimide (NHPI) and Co(II) under Mild Conditions

“…Unfortunately, despite the importance and attractiveness of this opinion, less attention has been paid to the development of new protocols for efficient oxidations of acetals to the corresponding esters using molecular oxygen. 15 It has been shown by the elegant works of Ishii and coworkers that the aerobic oxidation of various types of hydrocarbons using N-hydroxyphthalimide (NHPI) as a key radical generator can be achived. 16 Along this line, for example, oxidation of alkyl benzenes at normal pressure of O 2 and ambient temperature, 17 epoxidation of alkenes, 18 selective oxidation of sulfides to sulfoxides, 19 catalytic nitration of alkenes, 20 oxidation of alcohols, 21 and oxygen-ation of alkynes to a,b-acetylenic ketones 22 in the presence of NHPI as key catalyst were reported.…”

An Efficient Photoinduced Deprotection of Aromatic Acetals and Ketals

“…The side reaction is probably due to the formation and the reaction of singlet oxygen or of a photocreated reactive species with triplet oxygen. Direct oxidation of acetals to the corresponding esters involving molecular oxygen and a radical generator has been previously described [33].…”