ChemInform Abstract: Synthesis of Bishomobenzoctamine 2‐(9,10‐Dihydro‐9,10‐propanoanthracen‐9‐yl)‐N‐methylethanamine (IX)

The synthesis of the tetracyclic molecule 2-(9,10-dihydro-9,10-propano-anthracen-9-yl)-N-methylethanamine (2) as a homologue of the antidepressant 1-(9,10-dihydro-9,10-ethanoanthracen-9-yl)-N-methylmethaneamine (1) was described. The key intermediate 9-(prop-2-en-1-yl)-9,10-dihydro-9,10-propanoanthracen-12-one (7) was successfully synthesized via a [4+2] cycloaddition of α-bromoacrolein and 9-allyl-anthracene, followed by ring expansion and samarium diiodide deoxygenation.

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ChemInform Abstract: Synthesis of Bishomobenzoctamine 2‐(9,10‐Dihydro‐9,10‐propanoanthracen‐9‐yl)‐N‐methylethanamine (IX)

Abstract: Synthesis of Bishomobenzoctamine 2-(9,10-Dihydro-9,10-propanoanthracen-9-yl)-N-methylethanamine (IX) -[via an ultrasound-assisted [3 + 4] cycloaddition of allylanthracene (III) with tetrabromoacetone]. -(KARAMA*, U.; AL-SAIDEY, A.; ALMANSOUR, A. R.; J.

Cited by 2 publications

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Synthesis of [9, 10-dihydro-9-(4-methylaminobutyl)-9, 10-propanoanthracene] using Diels–Alder cycloaddition

Synthesis of [9, 10-dihydro-9-(4-methylaminobutyl)-9, 10-propanoanthracene] using Diels–Alder cycloaddition

Synthesis of 2-(9,10-Dihydro-9,10-propanoanthracen-9-yl)-N-methylethanamine via a [4+2] Cycloaddition

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