ChemInform Abstract: Synthesis of Bis‐α‐amino Acids Through Proline Catalyzed Asymmetric α‐Amination of Higher Homologues of Garner′s Aldehyde.

Abstract

Synthesis of Bis--amino Acids Through Proline Catalyzed Asymmetric -Amination of Higher Homologues of Garner's Aldehyde. -The convenient synthesis of bis--amino acid esters involves the proline catalyzed highly diastereoselective -hydrazination of aldehydes (I) with dibenzyl azodicarboxylate as the key step. -(PETAKAMSETTY, R.; DAS, R. P.; RAMAPANICKER*, R.; Tetrahedron 70 (2014) 50, 9554-9563, http://dx.