“…1,5‐Benzoheteroazepines are nitrogen‐ and sulfur‐containing seven‐membered heterocyclic compounds that exhibit a broad range of interesting biological activities, and numerous drug molecules have been developed based on 1,5‐benzothiazepines (Scheme ). For example, 1,5‐benzothiazepine‐based compounds have been reported to exhibit Ca 2+ channel antagonistic activity, CNS depressant activity, antiplatelet aggregator activity, anticancer activity, anti ‐HIV activity, antimicrobial activity, cardiovascular activity, and cholinesterase inhibitory activity . 1,5‐Benzodiazepines (seven‐membered heterocyclic compounds containing two nitrogen atoms) are widely used as anticonvulsant, anti‐anxiety, sedative, and antidepressants .…”