ChemInform Abstract: Synthesis of 3‐(1‐Methyl‐1H‐imidazol‐2‐ylthio)propanoic Acid and (E)‐3‐(1‐Methyl‐1H‐imidazol‐2‐ylthio)acrylic Acid.

Abstract

Synthesis of 3-(1-Methyl-1H-imidazol-2-ylthio)propanoic Acid and (E)-3-(1-Methyl-1H-imidazol-2-ylthio)acrylicAcid. -The E/Z ratio of the reaction products of (I) with methyl or tert-butyl propiolate (II) or (V) is studied (only some yields are given). -(HATTAN, C. M.; SHOJAIE, J.; LAU*, S. S.; ANDERS, M. W.; Synth. Commun. 43 (2013) 1, 1-8, http://dx.