ChemInform Abstract: Synthesis of 2‐Azido‐1,N6‐etheno and 2‐Azido Analogues of Deoxyadenosine as Nucleotide Photoaffinity Probes.

Abstract

Synthesis of 2-Azido-1,N6-etheno and 2-Azido Analogues of Deoxyadenosine as Nucleotide Photoaffinity Probes.-The title compounds (VIII) and (XII) are nucleotide photoaffinity labels used extensively to characterize ribonucleotide binding sites in purified enzymes and in vitro systems (for compound (X) no yield given). -(FLAHERTY, D.; BALSE, P.; LI, K.; MOORE, B. M.; DOUGHTY, M. B.; Nucleosides Nucleotides 14 (1995) 1-2, 65-76; Dep. Med. Chem., Univ. Kans., Lawrence, KS 66045, USA; EN)