ChemInform Abstract: Synthesis of 2,2‐Dimethyl‐1,2‐dihydrobenzo[f]isoquinolines Displaying Antifungal Activity.

Dimerization of 2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

“…We previously synthesized 3,3-dialkyl-3,4-dihydroisoquinolines and their benzo[f] derivatives and examined some properties of these compounds [2,3]. While continuing studies in this field, we found that heating of 2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline (I) in boiling toluene on exposure to air leads to the formation of dimer II.…”