ChemInform Abstract: Synthesis of 1H‐1,2,3‐Triazole Linked β‐Lactam—Isatin Bi‐Functional Hybrids and Preliminary Analysis of in vitro Activity Against the Protozoal Parasite Trichomonas vaginalis.

Abstract

Synthesis of 1H-1,2,3-Triazole Linked β-Lactam-Isatin Bi-Functional Hybrids and Preliminary Analysis of in vitro Activity Against the Protozoal Parasite Trichomonas vaginalis. -The compound (I) exhibits in vitro 100% growth inhibition at 100 μM against T. vaginalis and no cytotoxicity on cultured CHO-K1 cells. -(RAJ, R.; SINGH, P.; HABERKERN, N. T.; FAUCHER, R. M.; PATEL, N.; LAND, K. M.; KUMAR*, V.; Eur. J. Med. Chem. 63 (2013) 897-906, http://dx.