ChemInform Abstract: Synthesis of 1‐Substituted 5‐Aminoimidazole‐4‐carbaldehydes and 8‐Amino‐1‐(2‐fluorobenzyl)imidazo[4′,5′:5,6]pyrido[2,3‐d]pyrimidine.
Abstract:Synthesis of 1-Substituted 5-Aminoimidazole-4-carbaldehydes and 8-Amino-1-(2-fluorobenzyl)imidazo [4',5':5,6]pyrido[2,3-d]pyrimidine. -Various title compounds (III) are prepared as shown. The synthetic utility of the products is proved by transformation of (IIIe) to the pharmaceutically interesting ring system (VIII). -(BOOTH, BRIAN L.; CARPENTER, ROBERT A.; MORLOCK, GABY; MAHMOOD, ZAHID; PRITCHARD, ROBIN B.; Synthesis (2001) 16, 2393-2396; Dep. Chem., Univ. Manchester Inst. Sci. Technol., Manchester M60 1QD, … Show more
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