ChemInform Abstract: Synthesis of 1‐Indolyl Substituted β‐Carboline Natural Products and Discovery of Antimalarial and Cytotoxic Activities.

Abstract

A series of 1‐indolyl substituted β‐carbolines including the natural products hyrtiosulawesine (Ia), pityriacitrin (Ib) and pityriacitrin B (Ic) are prepared via a Pictet—Spengler condensation‐oxidation strategy from the corresponding indolyl aldehydes and substituted tryptamines.