ChemInform Abstract: Synthesis of 1,4‐Enamino Ketones by [3,3]‐Rearrangements of Dialkenylhydroxylamines.

Abstract

Synthesis of 1,4-Enamino Ketones by [3,3]-Rearrangements of Dialkenyl-hydroxylamines. -A new method for the synthesis of 1,4-enamino ketones through rearrangement of dialkenylhydroxylamines generated in situ by addition of N-alkenylnitrones to allenes is described. This route to dialkenylhydroxylamines has a broader scope than the Trofimov reaction. Additionally, the transformation of the obtained 1,4-enamino ketones to pyrroles, 1,4-diones, and furans is also shown. -(PECAK, W. H.; SON, J.; BURNSTINE, A. J.; ANDERSON*, L. L.; Org. Lett. 16 (2014) 13, 3440-3443, http://dx.