Abstract:Synthesis of 1,3-Disubstituted Azetidines via a Tandem Ring-Opening Ring-Closing Procedure. -Treatment of epoxide (I) with primary amines results in formation of the expected azetidines. When secondary amines are employed, symmetrical diamines are produced. -(MARCH-CORTIJOS, A.; SNAPE*, T. J.; TURNER, N. J.; Synlett 2012, 10, 1511-1515, http://dx.doi.org/10.1055/s-0031-1291014 ; Sch. Pharm. Pharm. Sci., Univ. Cent. Lancashire, Preston, Lancashire PR1 2HE, UK; Eng.) -Mais 40-119
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