ChemInform Abstract: Synthesis, Antifungal and Cytotoxic Activities of 2‐Aryl‐3‐((piperidin‐1‐yl)ethyl)thiazolidinones.

Abstract

Synthesis, Antifungal and Cytotoxic Activities of 2-Aryl-3-((piperidin-1-yl)ethyl)thiazolidinones. -Derivatives (IVc) and (IVf) exhibit activity against Rhodotorula sp. yeast that is 1.6 times higher than that of fluconazole. Moreover, all tested compounds show low toxic effects in vitro to Vero cells. -(KUNZLER, A.; NEUENFELDT, P. D.; DAS NEVES, A. M.; PEREIRA, C. M. P.; MARQUES, G. H.; NASCENTE, P. S.; FERNANDES, M. H. V.; HUEBNER, S. O.; CUNICO*, W.; Eur. J. Med. Chem. 64 (2013) 74-80, http://dx.