ChemInform Abstract: Synthesis and Structure of Fluorine‐Containing β‐Chlorovinyl Ketones.

Abstract

Upon chlorination with thionyl chloride, the unsymmetrically fluorinated β‐diketones (Ia) which have bulky alkyl substituents give only the Z‐configurated β‐chlorovinyl ketones (III).

The reaction of aryl and heteroarylhydrazines with aryl‐trifluoromethyl β‐diketones

“…Fluorinated -diketones (1a-f) and heteroarylhydazines (4, 5, 6) are well-known compounds often described in the literature: 1a (CAS 326-06-7) is a commercial product (Alfa), the others 1b (CAS 582-65-0), 1c (CAS 18931-60-7), 1d (CAS 18931-61-8), 1e (CAS 15191-68-1), 1f (CAS 35999-53-2) were synthesized according to literature procedures [12,20,21]. Phenylhydrazine (2) and p-nitrophenylhydrazine (3) are commercially available, 4 (CAS 20174-69-0), 5 (CAS 78364-55-3) and 6 (21703-52-6) were prepared according to literature procedures [22,23].…”