ChemInform Abstract: Synthesis and Structure‐Activity Relationships of 2‐(4‐Benzhydryl‐1‐ piperazinyl)‐1‐phenylethanols as New Calcium Blockers.

Abstract

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Synthesis, Anticancer Activity and Computational SAR Analysis of Acylsulfonylpiperazines Derivatives

“…Piperazines and substituted piperazines are important pharmacophores that are found in many drugs [14]. Piperazine scaffold acts on different pharmacological targets and is present in a broad range of biological active compounds, including several molecules against cancer [15][16][17][18][19][20][21], dual calcium antagonists [22], compounds with effects on dopaminergic neurotransmission [23] and HIV protease inhibitors [24,25]. …”