ChemInform Abstract: Synthesis and Optical Resolution of an Asymmetrically Substituted Calix(4)arene.

Abstract

Synthesis and Optical Resolution of an Asymmetrically SubstitutedCalix(4)arene. -Alkylation of the phenol (I) with the bisbromomethylphenol (II) yields the compound (III) which is converted into the tetrapropyl ether (±) -(VI) by subsequent reaction with propyl bromide (IV) in the presence of sodium hydride. (1H NMR spectra, CD spectra, optical resolution of ( VI)). -(SHINKAI, S.; ARIMURA, T.; KAWABATA, H.; MURAKAMI, H.; ARAKI, K.; IWAMOTO, K.; MATSUDA, T.; J.