ChemInform Abstract: Synthesis and Hypoglucamic Activity of Azolopyrimidine Derivatives.

Десенко, С. М.; Липсон, В. В.; Gorbenko, N. I.; Pivovarevich, L. P.; Ryndina, E. N.; Мороз, В. В.; Varavin, V. P.

doi:10.1002/chin.199544165

Cited by 3 publications

(2 citation statements)

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“…There are many reports about the biological activities of azoloazine derivatives. Such activities include antimicrobial,9b,9c antifungal,9b and hypoglycemic activities,9d in particular (DPP4) inhibition,9e as well as cardiovascular activity,9f HCV NS5B polymerase inhibition and replicon inhibition activity,9g cognition enhancement,9h inhibition of the translocation pore of Clostridium botulinum C2 toxin,9i etc.…”

Section: Introductionmentioning

confidence: 99%

Study of the Chemoselectivity of Multicomponent Heterocyclizations Involving 3‐Amino‐1,2,4‐triazole and Pyruvic Acids as Key Reagents, and Biological Activity of the Reaction Products

et al. 2015

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Three‐component reactions involving 3‐amino‐1,2,4‐triazole, aldehydes, including salicylic aldehydes, and pyruvic acids were studied in detail. The reaction pathway and products of the heterocyclizations could be changed by variation of the reaction parameters. The broad antimicrobial activity of the products was also studied. Compound 9d showed specific anti‐influenza virus (A/H1N1) activity, with an IC50 of 0.57 μM and a CC50 of >100 μM.

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Section: Introductionmentioning

confidence: 99%

Study of the Chemoselectivity of Multicomponent Heterocyclizations Involving 3‐Amino‐1,2,4‐triazole and Pyruvic Acids as Key Reagents, and Biological Activity of the Reaction Products

et al. 2015

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Section: Introductionmentioning

confidence: 99%

Sn^IV Porphyrin Scaffolds for Axially Bonded Multiporphyrin Arrays: Synthesis and Structure Elucidation by NMR Studies

Dvivedi¹,

Pareek²,

Ravikanth³

2014

Chemistry A European J

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A simple, one-step, supramolecular strategy was adopted to synthesize Sn(IV) -porphyrin-based axially bonded triads and higher oligomers by using meso-pyridyl Sn(IV) porphyrin, meso-hydroxyphenyl-21,23-dithiaporphyrin, and Ru(II) porphyrin as building blocks and employing complementary and non-interfering Sn(IV) O and Ru(II) ⋅⋅⋅N interactions. The multiporphyrin arrays are stable and robust and were purified by column chromatography. (1) H, (1) H-(1) H COSY and NOESY NMR spectroscopic studies were used to unequivocally deduce the molecular structures of Sn(IV) -porphyrin-based triads and higher oligomers. Absorption and electrochemical studies indicated weak interaction among the different porphyrin units in triads and higher oligomers, in support of the supramolecular nature of the arrays. Steady-state fluorescence studies on triads indicated the possibility of energy transfer in the singlet state from the basal Sn(IV) porphyrin to the axial 21,23-dithiaporphyrin. However, the higher oligomers were weakly fluorescent due to the presence of heavy Ru(II) porphyrin unit(s), which quench the fluorescence of the Sn(IV) porphyrin and 21,23-dithiaporphyrin units.

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Effective DABCO-catalyzed synthesis of new tetrazolo[1,5-a]pyrimidine analogs

et al. 2017

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In this study, an efficient multicomponent one-pot route is described for the DABCO-catalyzed synthesis of tetrazolo[1,5-a]pyrimidines. This synthesis strategy is based on the reaction of malononitrile and aldehydes with 5-aminotetrazole monohydrate using 1,4-diazabicyclo[2.2.2]octane (DABCO) in i-PrOH under reflux conditions. This protocol is a simple, green, and low-cost technique to prepare new compounds with potential medicinal properties.

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ChemInform Abstract: Synthesis and Hypoglucamic Activity of Azolopyrimidine Derivatives.

Cited by 3 publications

References 1 publication

Study of the Chemoselectivity of Multicomponent Heterocyclizations Involving 3‐Amino‐1,2,4‐triazole and Pyruvic Acids as Key Reagents, and Biological Activity of the Reaction Products

Study of the Chemoselectivity of Multicomponent Heterocyclizations Involving 3‐Amino‐1,2,4‐triazole and Pyruvic Acids as Key Reagents, and Biological Activity of the Reaction Products

Sn^IV Porphyrin Scaffolds for Axially Bonded Multiporphyrin Arrays: Synthesis and Structure Elucidation by NMR Studies

Effective DABCO-catalyzed synthesis of new tetrazolo[1,5-a]pyrimidine analogs

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ChemInform Abstract: Synthesis and Hypoglucamic Activity of Azolopyrimidine Derivatives.

Cited by 3 publications

References 1 publication

Study of the Chemoselectivity of Multicomponent Heterocyclizations Involving 3‐Amino‐1,2,4‐triazole and Pyruvic Acids as Key Reagents, and Biological Activity of the Reaction Products

Study of the Chemoselectivity of Multicomponent Heterocyclizations Involving 3‐Amino‐1,2,4‐triazole and Pyruvic Acids as Key Reagents, and Biological Activity of the Reaction Products

SnIV Porphyrin Scaffolds for Axially Bonded Multiporphyrin Arrays: Synthesis and Structure Elucidation by NMR Studies

Effective DABCO-catalyzed synthesis of new tetrazolo[1,5-a]pyrimidine analogs

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Product

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Sn^IV Porphyrin Scaffolds for Axially Bonded Multiporphyrin Arrays: Synthesis and Structure Elucidation by NMR Studies