ChemInform Abstract: Synthesis and Conformation of Hexahydroisoquino(1,2‐b) (3)benzazepines.

Abstract

Synthesis and Conformation of Hexahydroisoquino(1,2-b) (3)benzazepines.-A facile route for the synthesis of the title heterocycles (V) (6 examples) starting from (2-phenylethyl)amines (I) is given. Their conformation is investigated by NMR spectroscopic methods, X-ray analysis and dehydrogenation with mercury(II) acetate. -(CLEMENS, M.; MEISE, W.; HIMMEL, K.; JANSEN, M.; Liebigs Ann./Recl. (1997) 2, 447-457; Pharm.