“…Therefore Indole derivatives have captured the attention of organic synthetic chemists. Furthermore, indole and its analogs possess a wide spectrum of biological activities such as anti-inflammatory, 1,2 anti-microbial [3][4][5] , anti-bacterial, 6,7 anticonvulsant [8][9][10][11] and cardiovascular 12,13 effect. Indole is a popular component of fragrances and the precursors of many pharmaceuticals.…”