Abstract:Synthesis and Bioactivity of β-Lactamase Inhibitory Iodopenicillanic Acid Derivatives.-The methyl esters of (II) and (III) are tested as β-lactamase inhibitors against a variety of isolated β-lactamases; they inhibit at various concentrations. The sulfoxide stereochemistry of the methyl ester of the (R)-oxide (III) is determined from 1 H and 13 C NMR data. -(PETRIKOVICS, I.; JASZBERENYI, J. C.; HERNADI, F.; SZTARICSKAI, F.; BOGNAR, R.; BATTA, G.; BENESCH, L.; Acta Chim. Hung. 128 (1991) 1, 41-51; Dep. Chemothe… Show more
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