ChemInform Abstract: Synthesis and Application of Chalcones to the Preparation of Heterocyclic Structures.

Abstract

Synthesis and Application of Chalcones to the Preparation of Heterocyclic Structures. -Condensation of carbamate (I) with aromatic aldehydes can be performed under basic and acidic conditions. Resulting chalcones undergo further reaction with hydrazine, hydroxylamine, guanidine, and thiourea to afford pyrazole (VII), isoxazole (VI), and pyrimidine derivatives. With selenium dioxide the corresponding selenadiazole (XV) is formed. -(VELIKORODOV*, A. V.; IONOVA, V. A.; TEMIRBULATOVA, S. I.; TITOVA, O. L.; STEPKINA, N. N.; Russ. J. Org. Chem. 49 (2013) 11, 1610-1616, http://dx.doi.org/10.1134/S1070428013110080 ; Astrakhan State Univ., Astrakhan 414000, Russia; Eng.) -M. Bohle 26-035