ChemInform Abstract: Supramolecular Catalysis in the Synthesis of Substituted 1H‐Tetrazoles from Isonitriles by a Self‐Assembled Hexameric Capsule.

Abstract

Supramolecular Catalysis in the Synthesis of Substituted 1H-Tetrazoles from Isonitriles by a Self-Assembled Hexameric Capsule. -The synthesis of substituted 1H-tetrazoles from aliphatic or aromatic isonitriles and trimethylsilyl azide can be efficiently promoted by the hexameric capsule of resorcin[4]arene as a supramolecular self-assembled catalyst. The reaction is sensitive to the size and nature of the substrate and is driven by encapsulation of the reagents within the cavity of the supramolecular catalyst. -(GIUST, S.; LA SORELLA, G.; SPERNI, L.; FABRIS, F.; STRUKUL, G.; SCARSO*, A.; Asian J. Org. Chem. 4 (2015) 3, 217-220, http://dx.doi.org/10.1002/ajoc.201402229 ; Dip. Sci. Mol. Nanosist., Univ. Ca' Foscari, I-30123 Venezia, Italy; Eng.) -Nuesgen 29-191