ChemInform Abstract: Structure Elucidation and Total Synthesis of Kulkenon.

Abstract

Structure Elucidation and Total Synthesis of Kulkenon. -A combination of molecular modeling and NOE experiments is used to establish the revised configuration of (I) which is confirmed by its synthesis having a syn-selective vinylogous Kobayashi aldol reaction and an intramolecular Heck reaction as pivotal transformations. -(SYMKENBERG, G.; KALESSE*, M.; Angew. Chem., Int. Ed. 53 (2014) 7, 1795-1798, http://dx.