ChemInform Abstract: Stereoselective Synthesis of (+)‐Nephrosteranic Acid by Ring‐Closing Metathesis and Its Biological Evaluation.

Abstract

Stereoselective Synthesis of (+)-Nephrosteranic Acid by Ring-Closing Metathesis and Its Biological Evaluation. -A stereoselective synthesis of (+)-nephrosteranic acid (VIII) is presented. The biological evaluation shows that (VIII) shows potent antifungal, significant antibacterial and significant cytotoxic activities. -(PEREPOGU, A. K.; RAMAN, D.; MURTY, U. S. N.; RAO*, V. J.; Synth. Commun. 40 (2010) 5, 686-696, DOI:10.1080/00397910903011337; Org. Chem. Div., Indian Inst. Chem. Technol., Hyderabad 500 607, India; Eng.) -M. Bohle 32-205