ChemInform Abstract: Stereoisomeric Flavor Substances. Part 12. 3‐Methyl‐4‐octanolide ‐ “Quercuslactone, Whiskylactone” ‐ Structure and Properties of the Stereoisomers.

Abstract

The ketoester (III) is synthesized by reaction of pentanal (I) with the crotonate (II).

Synthesis, odour characteristics, and antibacterial activity of optically active cognac lactones

“…Therefore, the evaluation of the structure-function relationships of naturally occurring chiral flavour compounds is of significant interest. [7][8][9][10][11][12][13] Lactone stereoisomers possess varying odour characteristics and thresholds. [14][15][16] However, there exists a lack of information regarding the odour characteristics and thresholds for the stereoisomeric forms of cognac lactone.…”

“…It is well established that the biological activities of the enantiomers of these compounds differ. Therefore, the evaluation of the structure‐function relationships of naturally occurring chiral flavour compounds is of significant interest 7‐13 . Lactone stereoisomers possess varying odour characteristics and thresholds 14‐16 .…”