ChemInform Abstract: SPECTROSCOPIC STUDIES OF AMINO ACID DITHIOCARBAMATES WITH TRANSITION METALS COBALT(III), COPPER(II), NICKEL(II). II

Synthesis, Characterization, and Comparative in Vitro Cytotoxicity Studies of Platinum(II), Palladium(II), and Gold(III) Methylsarcosinedithiocarbamate Complexes

“…1,8 When a dithioester molecule is bonded to a metal center in a monodentate way through the thiocarbonyl sulfur donor atom, the ν(N-CSS) absorption band is shifted toward higher energies of about 20-30 cm -1 ; a larger shift (80-100 cm -1 ), as observed in our case, is indicative of the presence of chelated kS,kS′ complexes. 25,26 Regarding MSDT derivatives, this behavior cannot be observed, as we were not able to isolate the free methylsarcosinedithiocarbamate precursor, but the values of their ν(N-CSS) modes are in agreement with those reported in the literature for analogous metal derivatives of R-amino acid dithiocarbamates. [27][28][29] To discern the bonding type of the dithiocarbamate ligands in their complexes, the Bonati-Ugo method 30 is, by far, the most popular one.…”

“…On passing from a free dithiocarbamate ligand to its corresponding complexes, the ν(N−CSS) mode is shifted to higher energies, due to an increase of the carbon−nitrogen double bond character. , When a dithioester molecule is bonded to a metal center in a monodentate way through the thiocarbonyl sulfur donor atom, the ν(N−CSS) absorption band is shifted toward higher energies of about 20−30 cm -1 ; a larger shift (80−100 cm -1 ), as observed in our case, is indicative of the presence of chelated k S ,k S ‘ complexes. , Regarding MSDT derivatives, this behavior cannot be observed, as we were not able to isolate the free methylsarcosinedithiocarbamate precursor, but the values of their ν(N−CSS) modes are in agreement with those reported in the literature for analogous metal derivatives of α-amino acid dithiocarbamates. − …”