ChemInform Abstract: Silica Sulfuric Acid‐Catalyzed Friedel—Crafts Alkylation of Indoles with Nitro Olefins.

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Montmorillonite K10–Catalyzed Michael Addition of Indoles to Nitroolefins Under Solvent-Free Conditions

“…A variety of methods have been explored for the Michael addition reaction of indoles with a,b-substituted acceptors in the presence of protic or Lewis acids for the preparation of substituted indoles. [4][5][6][7][8][9][10][11][12][13][14][15] Nowadays, the ''greening'' of global chemical processes has become a major issue in chemical research. [16] While designing a new methodology under investigation, chemists always keep in mind the legislation on environmental friendliness in synthetic pathways and processes to prevent waste, avoid the use of auxiliary substances (e.g., solvents, separation agents), and minimize the potential for chemical accidents (e.g., explosion, fire).…”

“…1 Hz, 1H), 3.78 (s, 3H) 13. C NMR (100 MHz, CDCl 3 ): d C 154.2, 139.3, 131.6, 128.8, 127.6, 127.5, 126.4, 122.3, 114.1, 112.6, 112.1, 100.9, 79.4, 55.9, 41.5.…”

“…NMR (400 MHz) and13 C NMR (100 MHz) spectra were obtained for solution in CDCl 3 with Me 4 Si as internal standard on a Varian Mercury…”