ChemInform Abstract: Selectivity of N‐Aroyl‐N′‐arylthioureas Towards 2‐(1,3‐Dioxo‐1H‐inden‐2(3H)‐ylidene)malononitrile. New Synthesis of (Z)‐N‐((E)‐4‐Amino‐1‐aryl‐5‐cyano‐6‐oxo‐1H‐indeno[1,2‐d] [1,3]thiazepin2(6H)‐ylidene)‐4‐arylamides of Antitumor and Antioxidant Activities.

Abstract

Selectivity of N-Aroyl-N'-arylthioureas Towards 2-(1,3-Dioxo-1H-inden-2(3H)-ylidene)malononitrile. New Synthesis of (Z)-N-((E)-4-Amino-1-aryl-5-cyano--6-oxo-1H-indeno[1,2-d][1,3]thiazepin2(6H)-ylidene)-4-arylamides of Antitumorand Antioxidant Activities. -Some of the title thiazepine derivatives show effective antitumor, e.g. (IIIb), and/or antioxidative activities, e.g. (IIIb) and (IIId). -(ALY*, A. A.; BROWN, A. B.; RAMADAN, M.; ABDEL-AZIZ, M.; ABUO-RAHMA, G. E.-D. A. A.; RADWAN, M. F.; GAMAL-ELDEEN, A. M.; J. Heterocycl. Chem. 47 (2010) 3, 503-508,