ChemInform Abstract: Rhodium‐Catalyzed Asymmetric Olefin Hydrogenation by Easily Accessible Aniline‐ and Pyridine‐Derived Chiral Phosphites.

Abstract

Rhodium-Catalyzed Asymmetric Olefin Hydrogenation by Easily AccessibleAniline-and Pyridine-Derived Chiral Phosphites. -(R)-BINOL-derived bidentate P,N-phosphite ligands are prepared and tested in the hydrogenation of several prochiral olefins. The N-methylaniline-substituted ligand gives better enantioselectivity compared to the pyridine analogues. -(VALLIANATOU, K. A.; FRANK, D. J.; ANTONOPOULOU, G.; GOERGAKOPOULOS, S.; SIAPI, E.; ZERVOU, M.; KOSTAS*, I. D.; Tetrahedron Lett. 54 (2013) 5, 397-401, http://dx.