ChemInform Abstract: Regiospecific Lithiation of Phenoxazine Ortho to the Oxygen Atom. Synthesis of 4‐Mono‐ and 4,6‐Disubstituted Phenoxazine Derivatives.

Abstract

The N‐(1‐methylbenzyl) or N‐silylphenoxazines (I) are lithiated at C4 or C4 and C6, depending on the amount of butyllithium employed, and then quenched with various electrophiles, e.g. (II) or CO2 (VI), yielding mono‐ and disubstituted derivatives.