“…The reaction of ethyl phosphonites 420 with 2,2,2-trifluoroethyl iodide gave ethyl (2,2,2-trifluoroethyl)phosphinates 419 in moderate yields by the Michaelis−Arbuzov reaction. 462 Similarly, the reaction of ethyl diphenylphosphinite 421 with 2,2,2-trifluoroethyl iodide gave 2,2,2-trifluoroethyldiphenyl-phosphine oxide 422. Cyclenphosphorane 423 reacts with 2iodo-1,1,1-trifluoroethane in the presence of triethylamine at room temperature in tetrahydrofuran to form 1,1,1-trifluoroethylcyclenphosphorane 424 in 60% yield (Scheme 219).…”