ChemInform Abstract: REACTION OF PERFLUOROIODOALKANES WITH PHOSPHORUS(III) ACID ESTERS. IV. SYNTHESIS, NMR AND MASS SPECTRA OF ALKYLFLUOROALKYLPHOSPHINATES

Abstract

O,O‐Dialkyl‐ethyl‐phosphonite (I) reagieren mit den fluorierten Alkanen (II) und (IV) in einer Arbusov‐Reaktion zu den O‐Alkyl‐phosphinaten (III) bzw. (V).

Polyfluorinated Ethanes as Versatile Fluorinated C2-Building Blocks for Organic Synthesis

“…The reaction of ethyl phosphonites 420 with 2,2,2-trifluoroethyl iodide gave ethyl (2,2,2-trifluoroethyl)­phosphinates 419 in moderate yields by the Michaelis–Arbuzov reaction . Similarly, the reaction of ethyl diphenylphosphinite 421 with 2,2,2-trifluoroethyl iodide gave 2,2,2-trifluoroethyldiphenylphosphine oxide 422 .…”

“…The reaction of ethyl phosphonites 420 with 2,2,2-trifluoroethyl iodide gave ethyl (2,2,2-trifluoroethyl)phosphinates 419 in moderate yields by the Michaelis−Arbuzov reaction. 462 Similarly, the reaction of ethyl diphenylphosphinite 421 with 2,2,2-trifluoroethyl iodide gave 2,2,2-trifluoroethyldiphenyl-phosphine oxide 422. Cyclenphosphorane 423 reacts with 2iodo-1,1,1-trifluoroethane in the presence of triethylamine at room temperature in tetrahydrofuran to form 1,1,1-trifluoroethylcyclenphosphorane 424 in 60% yield (Scheme 219).…”