ChemInform Abstract: Reaction of N‐Silylated Lactams with Carboxylic Chlorides of Higher Carboxylic Acids and Alkaline Hydrolysis of the N‐Acyllactams Obtained.

Abstract

Reaction of N-Silylated Lactams with Carboxylic Chlorides of Higher Carboxylic Acids and Alkaline Hydrolysis of the N-AcyllactamsObtained.-Reaction of N-silyl lactams (III) with carboxylic chlorides provides smoothly the N-acylated lactams (V) which can be readily transformed into the corresponding N-acylated amino acids (VI) by alkaline hydrolysis in aqueous-alcoholic media.-(MIKHALKIN, A. P.; RYBALKA, I. G.; GORSHKOVA, L. V.; Zh.