ChemInform Abstract: Polymer Enzyme Conjugates as Chiral Ligands for Sharpless Dihydroxylation of Alkenes in Organic Solvents.

Abstract

Polymer Enzyme Conjugates as Chiral Ligands for Sharpless Dihydroxylation of Alkenes in Organic Solvents. -(KONIECZNY, S.; LEURS, M.; TILLER*, J. C.; ChemBioChem 16 (2015) 1, 83-90, http://dx.

Poly(2‐ethyloxazoline) as matrix for highly active electrospun enzymes in organic solvents

“…Goal of the present study was to explore the potential of poly(2-ethyloxazoline) (PEtOx) as matrix material for the activation of enzymes in electrospun nanofibers in organic solvents. We choose this polymer, because it was found enzyme friendly in solution, in amphiphilic polymer conetworks based on PEtOx, and even as enzyme-polymer conjugates to make the proteins organosoluble (Konieczny et al, 2012), reactive (Konieczny et al, 2014), and even applicable as ligands for organo-metal catalysis (Konieczny et al, 2015;Leurs et al, 2016). Al-Shehri et al (2003) have reported that enzymes can be electrospun from an aqueous solution of commercial PEtOx (M w ¼ 500,000 g/mol).…”