ChemInform Abstract: PEPARATION OF NEW VICINAL TRICARBONYL COMPOUNDS AND SOME OF THEIR SULFUR ANALOGS

Abstract

Die Malonamide (I) werden zu den Mesoxalsäureamiden (II) oxidiert, von denen (IIa) und (IIb) in die Mono‐ (III) bzw. Dischwefel‐Analoga (IV) und (V) übergeführt werden.

Design, Synthesis, and Resolution of Spirocyclic Bisoxindole-Based C2-Symmetric Diols

“…The corresponding N 1 , N 3 -dialkylmalonamides 3a – 3g were obtained with malonyl chloride in the presence of Et 3 N. We found that the addition sequence in this acylation step was critical for clean transformation and high yield. The direct transformation of the malonamides to their corresponding oxomalonamides seems to be challenging, as there are only limited reported examples . Although Zhang and co-workers developed a direct oxidative reaction for the synthesis of vicinal tricarbonyl amides with PIFA, low yields were obtained in our cases .…”