ChemInform Abstract: Palladium‐Catalyzed Oxidative C—H Bond Acylation of Acetanilides with Benzylic Alcohols.

Abstract

Palladium-Catalyzed Oxidative C-H Bond Acylation of Acetanilides with Benzylic Alcohols. -Oxidative coupling of benzylic alcohols (II) and (IV) with acetanilides (I) proceeds readily in the system tert-butyl hydroperoxide-TfOH-Pd(O-Ac)2 to afford o-aroylanilides (III) and (V), resp., in moderate to good yields. -(YUAN*, Y.; CHEN, D.; WANG, X.; Adv. Synth. Catal. 353 (2011) 18, 3373-3379, http://dx.doi.org/10.1002/adsc.201100417 ; Coll. Chem. Chem. Eng., Yangzhou Univ., Yangzhou, Jiangsu 225002, Peop. Rep. China; Eng.) -Mischke 18-041