ChemInform Abstract: Palladium‐Catalyzed ortho‐Selective C—F Activation of Polyfluoroarenes with Triethylsilane: A Facile Access to Partially Fluorinated Aromatics.

Abstract

The efficient and versatile title reaction gives access to fluoroarenes which are difficult to synthesize otherwise.

Palladium-Mediated Organofluorine Chemistry

“…260 The reaction of these derivatives with silanes led to selective ortho monohydrodefluorination (Scheme 86). By increasing the reaction temperature to 120 ˚C and the amount of silane, hydrodefluorination of both ortho fluorine atoms took place.…”