ChemInform Abstract: Paeonenoides D and E: Two New Nortriterpenoids from Paeonia lactiflora and Their Inhibitory Activities on NO Production.

Abstract

Two new nortriterpenoids, paeonenoides D (Ia) and E (Ib), are isolated from the roots of Paeonia lactiflora.

Antibacterial Activity of the Ethanol Extract of Paeonia lactiflora on Growth of Oral Bacteria

“…Drug combinations having synergistic interactions are generally considered as more effective and, therefore, preferable [19,20]. The major bioactive components of P. lactiflora include monoterpene glycosides, lignans, galloyl glucoses, nortriterpenoids, and phenolic compounds [16,17,22]. The extract of P. lactiflora has been demonstrated to exhibit anti-inflammatory, anti-spasmodic, and antiviral activities, in addition to lowering uric acid concentrations [14,15,22,23].…”

“…The major bioactive components of P. lactiflora include monoterpene glycosides, lignans, galloyl glucoses, nortriterpenoids, and phenolic compounds [16,17,22]. The extract of P. lactiflora has been demonstrated to exhibit anti-inflammatory, anti-spasmodic, and antiviral activities, in addition to lowering uric acid concentrations [14,15,22,23]. Recently, methyl gallate, paeonol, and 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose (PGG) with P. lactiflora root extract have been suggested as alternative sources of anti-Helicobacter pylori products because of their growth-inhibiting, bactericidal, and urease inhibitory effects [23].…”

Phytochemical Investigation of Egyptian Riverhemp: A Potential Source of Antileukemic Metabolites

“…e result was the isolation of 16 known compounds identified as liquidambaric lactone (3) [29], maslinic lactone (4) [30], oleanolic acid (5) [31], 11α,12α-epoxyoleanolic lactone (6) [32], oleanderolide (7) [33], stigmasterol glucoside (8) [34], P-aminophenol (9) [35], quercetin-3-O-α-L-rhamnopyranoside (10) [36], quercetin-3-O-β-Dglucopyranoside (11) [36], quercetin-3-O-α-L-arabinoside (12) [37], quercetin-3-O-β-D-xyloside (13) [37], mauritianin (14) [38] [42] (Fig. S4 and Table S3, Supplementary Materials).…”

<span>Progress in Terpenes from Genus&nbsp;</span><i>Paeonia</i>

“…[21] In 2014, paeoniside A (52) and paeoniside B (53), a glucose unit attached to the C-1 of the pinane skeleton via α-linkage, were obtained from root cortex of P. suffruticosa Andr., which exihibted against cyclooxygenase-1 and cyclooxygenase-2 enzymes. In addition, few isomers, paeoniflorin (55), isobenzoylpaeoniflorin (56) and epi-4-ethyl-benzoylpaeoniflorin (57) were isolated from P. lactiflora [11] and P. rubra. [17] The informations of those compounds were listed in Tables S1-S5 and Table S8.…”