ChemInform Abstract: Oxidative Activation of Dihydropyridine Amides to Reactive Acyl Donors.

Abstract

Oxidative Activation of Dihydropyridine Amides to Reactive Acyl Donors. -On-off switchable acyl donors in the form of dihydropyridine alkyl and arylamides are reacting with various primary and secondary aryl, benzyl, and alkyl amines as well as benzyl alcohols and benzylthiols. The method tolerates free carboxylic acid groups and is applicable to the preparation of peptides and 2,5-diketopiperazines. -(FUNDER, E. D.; TRADS, J. B.; GOTHELF*, K. V.; Org. Biomol. Chem. 13 (2015) 1, 185-198, http://dx.doi.org/10.1039/C4OB01931H ; Cent. DNA Nanotechnol., Dep. Chem., DK-8000 Aarhus, Den.; Eng.) -F. Schill 21-049