ChemInform Abstract: One‐Pot Four Component Synthesis of 4,6‐Disubstituted 3‐Cyano‐2‐pyridones in Polyethylene Glycol.

Synthesis of 4-aryl-6-phenyl-3-cyano-2-pyridones Using l-Proline as an Organocatalyst

“…In addition, 4,6-diaryl-3-cyano-2-pyridones were prepared by the reaction between 1,3-diaryl-2-propen-1-ones and cyanoacetamide using powdered KOH under microwave irradiation [23]. One of the less explored synthesis of 4-(substituted phenyl)-6-phenyl-3-cyano-2-pyridones is their synthesis from ethyl 2-cyano-3-(substituted phenyl) acrylates [24][25][26][27][28][29][30][31][32][33][34].…”