ChemInform Abstract: Novel Agents Effective Against Solid Tumors: The Diarylsulfonylureas. Synthesis, Activities, and Analysis of Quantitative Structure‐Activity Relationships.
Abstract:Novel Agents Effective Against Solid Tumors:The Diarylsulfonylureas.Synthesis, Activities, and Analysis of Quantitative Structure-Activity Relationships.-About 140 diarylsulfonylureas such as (III), (VI), or (X) are prepared by the three synthetic routes outlined in the reaction scheme. Of these compounds, the representative (VId) is the most potent derivative against solid tumors. -(HOWBERT, J. J.; GROSSMAN, C. S.; CROWELL, T. A.; RIEDER, B. J.; HARPER, R. W.; KRAMER, K. E.; TAO, E. V.; AIKINS, J.; POORE, G. … Show more
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