ChemInform Abstract: New Water‐Soluble Host Calixarenes Bearing Chiral Substituents.

Abstract

New Water-Soluble Host Calixarenes Bearing Chiral Substituents.-Sodium p-hydroxybenzenesulfonate (I) reacts with (S)-1-bromo-2-methylbutane (II) in the presence of a base to yield the methylbutoxybenzenesulfonate (III). Analogous reaction of (II) with the calix(4)arene (IV) leads to the formation of the tetrasulfonatotetrakis((S)-2-methylbutoxy)calix(4)arene (V). The corresponding calix(6)arene and calix (8)arene are synthesized in the same manner. The conformation and complexation properties of the calixarenes prepared are studied by means of CD-spectroscopy. -(ARIMURA, T.; KAWABATA, H.; MATSUDA, T.; MURAMATSU, T.; SATOH, H.; FUJIO, K.; MANABE, O.; SHINKAI, S.; J. Org. Chem. 56 (1991) 1, 301-306; Dep. Org.