ChemInform Abstract: New Synthetic Retinoids Obtained by Palladium‐Catalyzed Tandem Cyclization‐Hydride Capture Process.

Abstract

New Synthetic Retinoids Obtained by Palladium-Catalyzed TandemCyclization-Hydride Capture Process.-The first application of intramolecular Heck-type reaction to the preparation of new conformationally restricted retinoids having an asymmetric carbon atom is reported. An example of the use of enantiopure BINAP-Pd catalyst for the asymmetric synthesis of bioactive molecules is also given. -(DIAZ, P.; GENDRE, F.; STELLA, L.; CHARPENTIER, B.; Tetrahedron 54 (1998) 18, 4579-4590; CIRD GAL-DERMA, F-06902 Sophia Antipolis, Fr.; EN)