ChemInform Abstract: New Preparation of Benzylic Manganese Chlorides by the Direct Insertion of Magnesium into Benzylic Chlorides in the Presence of MnCl₂·2LiCl.

Abstract

Reactions of the new, conveniently prepared benzylic manganese reagents with aldehydes (II), acid chlorides (V), aryl bromides (VII) as well as nitrostyrene (IX) proceed without any additional transition metal. -(QUINIO, P.; BENISCHKE, A. D.; MOYEUX, A.; CAHIEZ, G.; KNOCHEL*, P.; Synlett 26 (2015) 4, 514-518, http://dx.

Iron-Catalyzed Cross-Coupling of Bis-(aryl)manganese Nucleophiles with Alkenyl Halides: Optimization and Mechanistic Investigations

“…Organomanganese species pioneered by Cahiez [15] often considerably reduce the amount of side reactions such as homo-coupling [16,17] and have proven to be excellent nucleophiles in various types of reactions [18][19][20][21][22][23][24] including cross-couplings [25,26]. Organomanganese species then constitute an interesting alternative to usual cross-coupling partners such as organomagnesium [27], organozinc [28], and organo-boronic esters, which may have genotoxic properties [29,30].…”