ChemInform Abstract: New NO‐Donors with Antithrombotic and Vasodilating Activities. Part 5. Oligonitroso Sydnone Imines.

Abstract

New NO-Donors with Antithrombotic and Vasodilating Activities. Part 5. Oligonitroso Sydnone Imines.-Bis-and tris-N-nitroso sydnone imines are synthesized using previously reported methods.The sydnone imine moiety is connected by aliphatic or aromatic bridges via C-4 (→ (I), (II)) or N-3 ( . fwdarw. (III)). The influence of chain length in the side chain on antithrombotic effects is studied and hexyl substituents show the best results. -(REHSE, K.; SCHLEIFER, K.-J.; MARTENS, A.; KAEMPFE, M.; Arch.