ChemInform Abstract: New Alkenyldiarylmethanes with Enhanced Potencies as anti‐HIV Agents which Act as Non‐Nucleoside Reverse Transcriptase Inhibitors.

Abstract

New Alkenyldiarylmethanes with Enhanced Potencies as anti-HIV Agents which Act as Non-Nucleoside Reverse Transcriptase Inhibitors. -Title compounds such as (I) (22 examples) are synthesized and evaluated for their inhibition of HIV-1 replication. The most potent compound is (Ia). -(CUSHMAN, M.; CASIMIRO-GARCIA, A.; HEJCHMAN, E.; RUELL, J. A.; HUANG, M.; SCHAEFFER, C.