ChemInform Abstract: Mixed Condensation of α‐Epoxy Ketones with Aldehydes. Part 1. Condensation of 4‐Methyl‐3,4‐epoxy‐2‐pentanone with Acetaldehyde and Propionaldehyde by Alkaline Catalysis.
Abstract:135ChemInform Abstract The base catalyzed condensation of the title compounds (I) and (II), which is studied for the first time, affords the derivatives (III). The yields for this step have been optimized. The best results are obtained if (I) and (IIa) or (IIb) are reacted in a 6:1 or 2:1 molar ratio, resp., under the conditions depicted in the scheme. The products (III) are easily dehydrated to give the unsaturated epoxy ketones (IV). The epoxy ketones (I) are found to be more reactive than the corresponding … Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.